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An important feature of acute viral hepatitis is the absence in most patients with hypoalbuminemia, splenomegaly, and significant compression of the liver, the disappearance of fever and often feel better in the icteric period (which is obviously due to the elimination of the pathogen), and, most importantly, regular appearance in blood in acute viral hepatitis type A or B antigenic determinants (markers), the causative agent of hepatitis and their disappearance during convalescence. Clinical observations and previously testified that there are two types of hepatitis with morphologically identical changes in the liver: the first type - with a short incubation period, highly contagious, and the fecal-oral transmission (hepatitis A, in modern terminology) and the second type - with a long incubation and at contagiousness and predominantly parenteral transmission (hepatitis pathogen hepatitis A (epidemic hepatitis) - RNA virus. This is the particle diameter of 27 nm belongs to the picornavirus family of enteroviruses, is localized in the cytoplasm of hepatocytes, spreads through fecal-oral route, in large quantities excreted in the feces 2 weeks before and within 1-2 weeks after the onset of acute viral hepatitis with a peak before the first symptoms.