The disease is a severe intrahepatic cholestasis, especially in pregnant women. Transition to the chronic form does not happen.

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Clinically severe form of acute viral hepatitis, neither A nor B is different from other acute viral hepatitis: there is weakness, abdominal pain, nausea and fever. Measures of prevention of acute and chronic viral hepatitis are a careful personal hygiene, widespread transition to a centralized sterilization of needles and syringes dry heat, and minimal use of blood, its components and the drugs and parenteral interventions.

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Clinical manifestations of the transition of acute viral hepatitis in the chronic form can be persistent asthenia - malaise, weakness, decrease disability, dyspeptic disorders, loss of appetite, nausea, intolerance to fat, alcohol and tobacco, persistent weight loss, often moderately enlarged, slightly painful, with a smooth surface liver. The main difficulty is the differential diagnosis of chronic hepatitis C developed after acute viral hepatitis syndrome after hepatic asthenia, dyspepsia, biliary dyskinesia, that is functional after hepatic disorders in the intact liver.